Autor(es): Gutmann L,Brick J F,Riggs J E

Resumo: In five patients with Guillain-Barré syndrome, clinical myokymia increased and myokymic burst amplification occurred when ionized Ca++ was lowered by hyperventilation. Myokymia decreased when ionized Ca++ was increased after IV infusion of CaCl2. These responses were absent or diminished in the four patients with myokymia due to brainstem lesions, suggesting that the blood-brain barrier impedes the effects of altered serum ionized Ca++ on axonal excitability. Altering serum Ca++ can distinguish peripheral and central myokymia.

Imprenta: Neurology, v. 36, n. 1, p. 126-130, 1986

Descritores: Guillain-Barre Syndrome - Pathogenesis

Data de publicação: 1986

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