Atypical Bickerstaff brainstem encephalitis: ataxic hypersomnolence without ophthalmoplegia.
Autor(es): Wakerley Benjamin R,Soon Derek,Chan Yee-Cheun,Yuki Nobuhiro
Resumo: Clinical and immunological evaluation of 'incomplete' Bickerstaff brainstem encephalitis (BBE). We studied two patients with postinfectious brainstem syndromes who presented at National University Hospital Singapore. Laboratory work-up included measurement of antiganglioside antibodies. Both patients displayed hypersomnolence and cerebellar-like ataxia in the absence of external ophthalmoplegia and carried high serum titres of IgG anti-GQ1b antibodies, strongly indicative of BBE. Ophthalmoplegia can be absent or incomplete in BBE, and the absence of this clinical feature should not exclude BBE from the clinicians' differential. Such cases of incomplete BBE could be defined as 'ataxic hypersomnolence without ophthalmoplegia'.
Palavras-Chave: EYE MOVEMENTS, GUILLAIN-BARRE SYNDROME, IMMUNOLOGY, NEUROPATHY
Imprenta: Journal of Neurology, Neurosurgery, and Psychiatry, v. 84, n. 11, p. 1206-1207, 2013
Identificador do objeto digital: 10.1136/jnnp-2013-304993
Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Clinical examination ; Guillain-Barre Syndrome - Immunology ; Guillain-Barre Syndrome - Public health
Data de publicação: 2013
