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An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome.

Autor(es)Sheikh Kazim A,Zhang Gang
ResumoAnti-glycan antibodies directed against gangliosides are now considered the major immune effectors that induce damage to intact nerve fibers in some variants of the monophasic neuropathic disorders that comprise Guillain-Barré syndrome. Recent experimental studies elucidating the complexity of anti-glycan antibody-mediated pathobiologic effects on intact and injured nerves undergoing repair are discussed.
ImprentaF1000 Biology Reports, v. 2, 2010
Identificador do Objeto Digital10.3410/B2-21
DescritoresGuillain-Barre Syndrome - Antibodies
Data de Publicação:2010