An update on pathobiologic roles of anti-glycan antibodies in Guillain-Barré syndrome.

Autor(es): Sheikh Kazim A,Zhang Gang

Resumo: Anti-glycan antibodies directed against gangliosides are now considered the major immune effectors that induce damage to intact nerve fibers in some variants of the monophasic neuropathic disorders that comprise Guillain-Barré syndrome. Recent experimental studies elucidating the complexity of anti-glycan antibody-mediated pathobiologic effects on intact and injured nerves undergoing repair are discussed.

Imprenta: F1000 Biology Reports, v. 2, 2010

Identificador do objeto digital: 10.3410/B2-21

Descritores: Guillain-Barre Syndrome - Antibodies

Data de publicação: 2010