An adult case of Fisher syndrome subsequent to Mycoplasma pneumoniae infection.

Autor(es): Lee So Yeon,Lee Yong Hoon,Chun Bo Young,Lee Shin Yup,Cha Seung Ick,Kim Chang Ho,Park Jae Yong,Lee Jaehee

Resumo: Reported herein is an adult case of Fisher syndrome (FS) that occurred as a complication during the course of community-acquired pneumonia caused by Mycoplasma pneumoniae. A 38-yr-old man who had been treated with antibiotics for serologically proven M. pneumoniae pneumonia presented with a sudden onset of diplopia, ataxic gait, and areflexia. A thorough evaluation including brain imaging, cerebrospinal fluid examination, a nerve conduction study, and detection of serum anti-ganglioside GQ1b antibody titers led to the diagnosis of FS. Antibiotic treatment of the underlying M. pneumoniae pneumonia was maintained without additional immunomodulatory agents. A complete and spontaneous resolution of neurologic abnormalities was observed within 1 month, accompanied by resolution of lung lesions.

Palavras-Chave: Anti-GQ1b Antibody, Fisher Syndrome, Mycoplasma pneumoniae

Imprenta: Journal of Korean Medical Science, v. 28, n. 1, p. 152-155, 2013

Identificador do objeto digital: 10.3346/jkms.2013.28.1.152

Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Immunology

Data de publicação: 2013