Autor(es)Koga M,Koike S,Hirata K,Yuki N

ResumoHaemophilus influenzae is considered a causative agent of Guillain-Barré syndrome (GBS) and Fisher syndrome, but the frequency of this infection in GBS is controversial. To determine whether isolation of H influenzae indicates it is a causative agent in GBS and Fisher syndrome. Four (15%) of 27 patients with GBS and Fisher syndrome in whom H influenzae was isolated were also seropositive for Campylobacter jejuni. Antiganglioside IgG antibodies in these four patients did not cross react with their H influenzae lipo-oligosaccharides, whereas antiganglioside antibodies in the four patients with positive serology for H influenzae did. The findings suggest that H influenzae isolation is not always indicative of the causative agent in these syndromes and that tests for other infections should be made, even in cases of positive culture.

ImprentaJournal of Neurology, Neurosurgery, and Psychiatry, v. 76, n. 12, p. 1736-1738, 2005

DescritoresGuillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Serology

Data de Publicação:2005