Acute transverse myelopathy successfully treated with plasmapheresis and prednisone in a patient with primary Sjögren's syndrome.
Autor(es): Konttinen Y T,Kinnunen E,von Bonsdorff M,Lillqvist P,Immonen I,Bergroth V,Segerberg-Konttinen M,Friman C
Resumo: We report a case of acute transverse myelopathy in a patient with primary Sjögren's syndrome of 3 years duration. Our patient's acute transverse myelopathy developed within 1 week and resulted in complete paraparesis below the mamillary level. Extensive laboratory investigation ruled out viral, bacterial, and fungal etiology, Guillain-Barré syndrome, poliomyelitis, and multiple sclerosis. At diagnosis, treatment was initiated immediately with prednisone (80 mg/day) and plasmapheresis, which was performed as a first-aid measure. Improvement was noted as early as 10 days after the start of therapy. Within 5 1/2 months of the first symptoms of paralysis, the patient walked without difficulty and returned to her normal activities. A causal relationship between plasmapheresis/prednisone therapy and recovery has not been proven but merits further consideration.
Imprenta: Arthritis and Rheumatism, v. 30, n. 3, p. 339-344, 1987
Identificador do objeto digital: 10.1002/art.1780300314
Descritores: Guillain-Barre Syndrome - Pathogenesis
Data de publicação: 1987
