Autor(es): Schuller E

Resumo: Short term and long term beneficial effects of IgG administration have been studied in 4 groups of neuro-immunological diseases: Polymyositis, dermatomyositis and myasthenia. Peripheral neuropathies (myelinopathies), primarily in Guillain-Barré syndrome and in chronic inflammatory polyneuropathy. Children intractable Epilepsy. Multiple Sclerosis. Actual results are in favor of an objective and marked improvement (after 1 or 2 months) in the first 2 groups using intravenous IgG. In M.S. patients, the short term treatment of bouts (especially: optic neuritis) seems promising. Results of the only one long term (later than 10 years) trial are in favor of a significant slowing of the progression of M.S. comparatively to the predictive curve of disease.

Imprenta: Transfusion Clinique et Biologique : Journal de la Socie?te? Franc?aise de Transfusion Sanguine, v. 2, n. 1, p. 57-66, 1995

Identificador do objeto digital: 10.1016/S1246-7820(05)80023-0

Descritores: Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies

Data de publicação: 1995