Molecular and immunological biomarkers to predict IVIg response.
Autor(es): Galeotti Caroline.; Kaveri Srini V.; Bayry Jagadeesh
Resumo: Some patients with autoimmune and inflammatory diseases treated with intravenous immunoglobulin G (IVIg) as a first line therapy are refractory. Identification of predictive biomarker(s) to segregate responders and non-responders to IVIg therapy remains critical. A number of biomarkers, particularly in Kawasaki disease, have shown potential for predicting response to IVIg.
Palavras-Chave: Fc? receptor, Guillain-Barré syndrome, Kawasaki disease, cytokines, immune thrombocytopenia, intravenous immunoglobulin
Imprenta: Trends in Molecular Medicine, v. 21, n. 3, p. 145-147, 2015
Identificador do objeto digital: 10.1016/j.molmed.2015.01.005
Descritores: Guillain-Barre Syndrome - Biosynthesis ; Guillain-Barre Syndrome - DNA ; Guillain-Barre Syndrome - Immune response ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies ; Guillain-Barre Syndrome - Cytokines ; Guillain-Barre Syndrome - Immunopathology
Data de publicação: 2015
