Leprosy with Guillain Barre Syndrome: a new neurologic manifestation?
Autor(es): Grover Chander; Kubba Samir; Nanda Soni; Kumar Vijay; Reddy Belum Siva Nagi
Resumo: A 19-year-old female patient of lepromatous leprosy with Type II reaction, on multidrug therapy and prednisolone, presented with acute onset flaccid quadriparesis. The cerebrospinal fluid examination revealed albumino-cytologic dissociation. Nerve biopsy showed infiltration with lepra bacilli, features of vasculitis, and demyelination. There were no other identifiable precipitating factors for Guillain Barre Syndrome in this patient. Her condition improved without any steroid therapy. This case emphasizes the hypothesis that cell injury caused by Type II reaction can expose neural antigens and incite an autoimmune reaction in the form of Guillain Barre Syndrome.
Imprenta: The Journal of Dermatology, v. 31, n. 2, p. 119-123, 2004
Identificador do objeto digital: 10.1111/j.1346-8138.2004.tb00520.x
Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis
Data de publicação: 2004
