Autor(es): Vasconcellos E.; Smith M.

Resumo: Krabbe disease is characterized by abnormal breakdown and turnover of myelin, leading to extensive demyelination in both the peripheral and central nervous systems. A 7-month-old infant with early-onset Krabbe disease had deceptively normal head images, but spinal MRI demonstrated abnormal gadolinium enhancement of the lumbosacral sacral nerve roots and cauda equina such as that seen in Guillain-Barré syndrome. Abnormal enhancement in spinal MRI has not been previously described in patients with leukodystrophies.

Imprenta: Pediatric Neurology, v. 19, n. 2, p. 151-152, 1998

Identificador do objeto digital: 10.1016/S0887-8994(98)00033-2

Descritores: Guillain-Barre Syndrome - Cell ; Guillain-Barre Syndrome - Cytopathology

Data de publicação: 1998