Significance of phrenic nerve electrophysiological abnormalities in Guillain-Barré syndrome

Autor(es): Durand M C,Prigent H,Sivadon-Tardy V,Orlikowski D,Caudie C,Devaux C,Clair B,Gaillard J-L,Lofaso F,Raphael J-C,Sharshar T

Resumo: The authors investigated whether the amplitude and latency of diaphragm compound muscle action potential helped predict respiratory failure in Guillain-Barré syndrome. Both variables were significantly but weakly correlated with vital capacity (VC) and were similar in unventilated (n = 60) and ventilated (n = 10) patients. In ventilated patients, motor loss severity, progression, and VC reduction were significantly greater, and bulbar dysfunction was more common. Predicting respiratory failure must rely on clinical features and VC.

Imprenta: Neurology, v. 65, n. 10, p. 1646-1649, 2005

Identificador do objeto digital: 10.1212/01.wnl.0000184589.62101.b9

Descritores: Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Public health

Data de publicação: 2005