Neuropathologic findings in a Guillain-Barré patient with strokes after IVIg therapy.

Autor(es): Byrne N. P.; Henry J. C.; Herrmann D. N.; Abdelhalim A. N.; Shrier D. A.; Francis C. W.; Powers J. M.

Resumo: Strokes have been rarely associated with immunoglobulin G (IVIg) therapy. A 70-year-old woman with stable polycythemia vera developed Guillain-Barré syndrome and received IVIg, 8 days following which she became comatose due to bilaterally symmetric cerebral infarcts. Autopsy showed intravascular aggregates of fibrin-IgG but also platelets and a necrotizing microangiopathy in the infarcts.

Imprenta: Neurology, v. 59, n. 3, p. 458-461, 2002

Identificador do objeto digital: 10.1212/WNL.59.3.458

Descritores: Guillain-Barre Syndrome - Cytopathology ; Guillain-Barre Syndrome - Pathogenesis ; Guillain-Barre Syndrome - Proteins ; Guillain-Barre Syndrome - Antibodies

Data de publicação: 2002